Your B5 should cruise vibe-free at 65-ish but being a 2016 it may not be fully run in yet. That can take 600-1200 miles, or more. If you put the C5's 18T cog on, or even the 19T, then you would increase the potential top speed. But it would reduce power by using lower revs; Catch 22. If you up the gearing you reduce the revs needed for 60mph but you reduce the power so it may not pull as well. Acceleration or top speed? - it's a trade off. Personally I prefer more low down torque, I seldom feel the need to go flat out and lie on the tank.
I have lightly tuned my C5 with exhaust, K&N and PCV, but it can and will cruise at 70+mph without feeling like a food blender. It is on standard gearing with 2200+miles on the clock.
Imo better to cure the vibration. - Complete its running-in fully. This is very important to reduce vibes. - Ensure the head stay is nice and tight. - Loosen the front engine mounts, run the motor (don't ride it), then re-tighten. (I have not needed to do this but it re-seats the engine). If the exhaust to head clamp is loose you will not only hear it but your eyeballs will pop out, and that is a point - the entire exhaust system needs to be hung on the frame in a neutral position not stretched and forced to fit, or that will transmit a lot of vibration.
You can change the silencer on the stock ECU which will give a small boost of power and may feel smoother. If you change the entire exhaust system and add the K&N it confuses the ECU and then you need the PCV to fix the mix. Not cheap and something to be done only when it is run in.
Most of the vibration comes up the front tube of the frame and the engine is a stressed member of the frame. The bike is noted for loosening nuts and bolts when new so re-tighten everything and use Loctite.
I have also spread-sheeted the gears with stock gears and stock tyres - both the B5 and C5 are 17mph/1000rpm in 5th gear. This gives a top speed of 83mph at 5000rpm. The rev-limiter is 5500rpm (91mph) but I very much doubt it will produce enough power to pull much over 5100rpm (85mph) in top due to wind resistance (increases with the square of velocity).
There are some discrepancies on sources giving the outer diameter of the RoadRider and SkidMaster tyres, I used Avon's numbers
This one
https://www.youtube.com/watch?v=Nn7uwaG7kPs at about 5:00 has my C5 going uphill to about 70mph but it's not at full chat because the road is far from flat, it bucks and kicks all over the place, besides which it leads into a blind junction on an s-bend. Watch the tacho